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Senecionine – a pyrrolizidine alkaloid

The phytotoxin Senecionine is one of over 660 known secondary metabolites of the pyrrolizidine alkaloid (PA) subclass. It is one of the major compounds found in plants of the genus Senecio (ragwort) belonging to the Asteraceae family. In total, PAs have been found in 350 different plant species but estimations suggest they may occur in about 6,000 species or 3% of all flowering plants worldwide.